Best Collagen Face Cream for Women Over 50 (Or Any Age!) [2021]

Best collagen face creams for women over 50

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No one appreciates the deep wrinkles, fine lines, dryness and sagging skin on their face as the years go by. 

Quickly, collagen protein is the most abundant protein in the human body. It's often referred to as the 'glue' or 'scaffolding' that holds the body today. Collagen is especially concentrated in the skin cells. 

Unfortunately, as you approached your late 20s, your body slowed down collagen production to the tune of 1% each year.

It gets worse...

During and after menopause, collagen levels continue to fall--at a greater rate.

With less collagen in the skin, your skin's firmness, hydration and skin elasticity start to lessen.

Instead you'll experience dry skin, fine lines, uneven skin tone and dark spots. 

Truthfully, no collagen cream is going to make you look like you're in your teens, but you do have some control over holding off those signs of aging by encouraging collagen production.

That's why we did this in-depth review on the best collagen face cream for women over 50, and frankly, for any age! 

Let's get started...

Our Winner For Best Collagen Face Cream for Women

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Kleem Organics Advanced Retinol Moisturizer

Our Rating

Beauty starts from's a detailed review of the best hydrolyzed collagen peptides supplements for wrinkles on the market today

Rating Chart Best Collagen Face Cream for Women Over 50

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Our Rating


Kleem Organics Anti-Aging Retinol Moisturizer Cream

RAYA HA + Collagen Serum

VIJUVE 45% Vitamin C Serum Collagen Peptides

InstaNatural Collagen Night Anti Aging Cream

Best Collagen Face Cream for Women Over 50 Reviews

1. Kleem Organics Anti-Aging Retinol Cream

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Highlighted as the top anti-aging cream in 2019 by Amazon, this product is one to look at more closely to see if it's right for you.

First, Kleem states their moisturizer is guaranteed to provide deeper hydration within 72 hours.

The product's ability to increase collagen and elastin production can plump up and tighten skin.

As a result, wrinkles can smooth out and firm sagging skin.

Second, Kleem includes 2.5% retinol, hyaluronic acid, vitamin E, green tea and jojoba oil.

All of these natural ingredients will help your skin to remain well hydrated, appear brighter and tighter and softer. 

Third, they use both organic and natural ingredients inside this skin-firming cream.

It is parabens and alcohol free, manufactured in the USA in an FDA-approved facility and endorsed by PETA as being cruelty-free.

More importantly, it is designed to not clog pores or make skin feel and look oily.

Therefore, if you choose, you can apply makeup or sunscreen over the moisturizer.

Overall, thousands of users reported they loved the feel and results of using this product.


  • Company guarantees deeper hydration
  • Lightweight and effective
  • Collagen and elastin producing ingredients
  • All organic and natural ingredients
  • Light orange-y scent

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2. RAYA HA+ Collagen Anti-Aging Treatment

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Technically not a traditional 'cream', this version of the HA + Collagen face treatment is available in a serum for all skin types. They actually call it a 'cream serum'.

TIP: the company does offer a traditional collagen cream with the same general formula, but geared more towards dry skin. For this reason, oily or combination skin type would be better suited to the cream serum version we are reviewing here.

First, RAYA products are manufactured in the United States, in a state-of-the-art 10,000 sq. ft. manufacturing, FDA-registered facility. Further, Raya HA + Collagen Serum is is paraben free, contains only natural ingredients and is not tested on animals.

RAYA HA + Collagen's main ingredient is marine collagen. Marine collagen is sourced from fish and contains a high percentage of Type I collagen. Type I is the largest and most common type of collagen found in our bodies and primarily is found in the skin.

Hydrolyzed marine collagen peptides help give strength to skin, reduce and slow down the formation of fine lines and wrinkles. In addition to marine collagen, aloe vera, wheat placenta (if you're sensitive to wheat, you'll want to avoid this product) and glycerin are added to the serum. 

The smell of the RAYA Serum is almost non existent and absorbs into the skin without leaving a greasy feeling. As a result, makeup can easily be applied over the serum.

Reviewers report they love the feeling of the product on their face and noticed reductions in fine lines and wrinkles. In addition, they also report a feeling of tightness, plumpness and less sagging (especially in older women).

The buyers of RAYA collagen serum appreciate the excellent packaging. In addition, as an added bonus, RAYA tends to send free samples of other products to try with each order.


  • Paraben free, natural ingredients, no animal testing
  • Users love the product
  • Manufactured in the United States
  • Made with highly bio-available marine collagen
  • Atractive packaging, free samples
  • Practically no scent
  • Contains wheat

3. VIJUVE Vitamin C and Collagen Peptides

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Vijuve offers a multi-use product for face, eyes, neck and chest. Often, it's your neck and chest that start to show your age first (and two areas that are frequently overlooked in women's skin care health).

Manufactured in the United States, VIJUVE skin-care serum is not tested on animals, has no parabens, oil or fragrance. The company indicates their product is safe for all ages and skin types.

Actually, this skincare product contains proprietary synthetic collage peptides, ARGERILENE & REPROAGE.  

These synthetic collagen peptides help soften lines and wrinkles in the forehead and/or around the eyes. These peptides have shown terrific results in studies and will be used in more and more skincare products in the future.

Furthermore, VIJUVE offers a high concentration of vitamin C at 45%. 

As indicated in this study, Vitamin C is necessary to for collagen synthesis. Vitamin C also happens to help brighten and lighten age spots in older skin, reduces inflammation, heals blemishes and sun damage from UV rays and free radicals. It's a must for any skincare routine.

Vijuve includes not one, but two types of hyaluronic acid. Hyaluronic acid naturally occurs in your body. Its job is to retain water, which keeps your skin hydrated. The dual attack of the two types of hyaluronic acid penetrates the skin quickly and moisturizes the skin at a faster rate.

Finally, for best results, the company recommends the VIJUVE Anti Aging Face Massager to use along with their products. However, the massager is NOT needed or required to use this serum.

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  • Can be used on face, under eyes, neck and chest
  • Manufactured in the US, no parabens, oils or fragrance added
  • Contains proprietary collagen-like peptides
  • includes a high concentration of vitamin C and two types of hyaluronic acid
  • There is a light scent to this product

4. InstaNatural Collagen Night Anti Aging Cream

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Many women use an anti-aging cream at night for convenience and InstaNatural is a good choice if that's how you want to reverse or stop the effects of aging. 

First, InstaNatural Collagen Night Cream doesn't contain a specific collagen type. Instead, it contains commercially available Detoskin.  Detoskin is peoney root extract that supports the creation of collagen type III and repels MMP that destroys collagen.

Furthermore, Detoskin has been clinically-proven to accelerate cell turnover and reduce other signs of aging such as wrinkles, roughness and uneven tone.

In addition to Detoskin, the night cream contains Rosehip Seed Oil. Rosehip Seed Oil provides moisture to skin and improves skin's tone and texture. When we have enough moisture in our skin, it helps hold off the signs of aging and our skin feels 'plumper'.

Other interesting ingredients include vitamin C,  which is known to brighten, tighten and even out skin tone (and is required to create new collagen).

Finally, InstaNatural includes hyaluronic acid which holds moisture in our skin, which helps soften lines and wrinkles. 

InstaNatural believes in using as many organic, natural and naturally-derived products as possible (and if not natural, would rather leave them out), and also offers a 120-day 100% satisfaction guarantee. 

Finally, the InstaNatural Night Cream is made in the US in an FDA-registered facility.


  • Unique ingredients: Detoskin and rosehip seed oil
  • Hyaluronic acid and vitamin C are also added
  • Convenient night-time application
  • Try risk-free with a 100% money-back guarantee
  • Cream has a thinner consistency
  • There is a light scent to this moisturizer


The editor's final recommendation for the best collagen face cream for women over 50 (or any age!) is Kleem Organics Retinol Moisturizer.

Our beauty editor loves this all-natural ingredient powerhouse of an age-defying retinol moisturizer with collagen-encouraging peptides suitable for all skin types.

We hope this in-depth review helps you the confidence to try the best collagen face cream for women over 50, Kleem Organics Retinols Moisturizer

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